| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 27391 | Journal of Photochemistry and Photobiology A: Chemistry | 2011 | 10 Pages |
The synthesis, characterization, photophysical and photochemical properties of the new metal-free and zinc (II) phthalocyanines tetra-substituted at the peripheral (complexes 3a and 3b) and non-peripheral (complexes 4a and 4b) positions with 7,8-(12-crown-4)-3-(4-oxyphenyl)coumarin groups are reported for the first time. The new compounds have been characterized by elemental analysis, FT-IR, 1H NMR, electronic spectroscopy and mass spectra. General trends are described for photodegradation, singlet oxygen and fluorescence quantum yields, and fluorescence lifetimes of these compounds in dimethylsulphoxide (DMSO). Photophysical and photochemical properties of phthalocyanine complexes are very useful for photodynamic therapy (PDT) applications. The singlet oxygen quantum yields (ΦΔ) ranged from 0.11 to 0.80 are indicating the potential of the complexes as photosensitizers in applications of PDT.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Synthesis, characterization, photophysical and photochemical properties of the new metal-free and zinc (II) phthalocyanines tetra-substituted at the peripheral (complexes 3a and 3b) and non-peripheral (complexes 4a and 4b) positions with 7,8-(12-crown-4)-3-(4-oxyphenyl)coumarin groups. ► Photophysical and photochemical properties in DMSO. ► Ground state electronic absorption and fluorescence spectra. ► Photodynamic therapy.
