| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 27543 | Journal of Photochemistry and Photobiology A: Chemistry | 2011 | 8 Pages |
Abstract
In this study we have tried to explore structure–dynamics relationship of FAD with the help of time resolved fluorescence studies over five orders in time scale from several hundreds of femtosecond to nanosecond. We found that FAD has conformational flexibility, due to which it exhibits several distinct dynamics in the pH range between 0.5 and 13.0. Our lifetime and anisotropy results confirm conformational changes of FAD at pH = 3.0 and pH = 10.0.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Flavin adenine dinucleotide. ► pH dependent conformational dynamics. ► Time correlated single photon counting. ► Femtosecond up-conversion. ► Time resolved fluorescence anisotropy.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Abhigyan Sengupta, Rahul V. Khade, Partha Hazra,