Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2764637 | Journal of Critical Care | 2013 | 7 Pages |
Abstract
Dornase alfa does not improve the appearance of atelectasis on chest radiographs, or the “Total Chest X-Ray Score" over the first 5 days of treatment in mechanically ventilated patients. The intervention group's higher rate of extubation during the first 24 hours as well as its improved oxygenation on day 5 were likely chance findings given the multiple potential confounders for extubation and low study power.
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Authors
Jessica Nutik MD, MPH, Pierre MD, Michael PhD, Kevin P. MD, MPH,