Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2765223 | Journal of Critical Care | 2011 | 9 Pages |
Abstract
If PROTECT shows that LMWH is more effective than UFH, this trial will change practice in that LMWH may be the anticoagulant thromboprophylaxis of choice for this population. If the results show that UFH is as effective or more effective than LMWH, intensivists in many parts of the world may continue to use UFH, whereas those currently using LMWH may reconsider and change to use UFH. Unfavorable consequences such as major bleeding, ease of use, and the costs of complications will also factor into such decisions.
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Authors
Deborah Cook, Maureen Meade, Gordon Guyatt, Stephen D. Walter, Diane Heels-Ansdell, William Geerts, Theodore E. Warkentin, D. Jamie Cooper, Nicole Zytaruk, Shirley Vallance, Otavio Berwanger, Marcelo Rocha, Ismael Qushmaq, Mark Crowther,