Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2765492 | Journal of Critical Care | 2010 | 16 Pages |
Abstract
This meta-analysis demonstrated a protective effect for statins in patients with sepsis and/or other infections compared to placebo for various infection-related outcomes. However, our results are limited by the cohort design of the selected studies and the degree of heterogeneity among them, and as a result, further randomized trials are needed to validate the use of statins for sepsis and/or other infections.
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Authors
Surinder MD, CCFP, Aaron MD, J. Mark MB, MD, FRCP(I), FRCP(C), FACCP, Mahyar PharmD, MSc (Epid), John MD, FRCPC,