Accuracy of clinical diagnosis and decision to commence intravenous prostaglandin E1 in neonates presenting with hypoxemia in a transport setting

Although the accuracy of a diagnosis of CHD and the decision to initiate PGE1 was high, 12% of neonates with a duct-dependent CHD were transported without commencement of PGE1. Lower thresholds for PGE1 administration to hypoxemic neonates may potentially improve preoperative stabilization and minimize neonatal morbidity.