Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2775282 | Experimental and Molecular Pathology | 2013 | 7 Pages |
Abstract
B-Raf is one of the more commonly mutated proto-oncogenes implicated in the development of cancers. In this review, we consider the mechanisms and clinical impacts of B-Raf mutations in cancer and discuss the implications for the patient in melanoma, thyroid cancer and colorectal cancer, where B-Raf mutations are particularly common.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Clinical Biochemistry
Authors
M.A. Rahman, A. Salajegheh, R.A. Smith, A.K.-Y. Lam,