Article ID Journal Published Year Pages File Type
2775494 Experimental and Molecular Pathology 2010 7 Pages PDF
Abstract
► Schistosoma mansoni, produces a hypoxic tissue microenvironment. ► Schistosoma mansoni infection induces HIF-1α and VEGF expression. ► Schistosoma mansoni infected murine liver, intestine and spleen showed pimonidazole binding and HIF-1α and VEGF expression. ► Schistosoma mansoni infection generates hypoxia and HIF-1α and VEGF expression. ► A hypoxia-dependent HIF-1α activation in Schistosoma mansoni infected mice.
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