| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2862607 | American Journal of Hypertension | 2007 | 7 Pages |
Abstract
Compared with fresh resistance arterioles and aorta, cultured VSMCs exhibit changes in PLC-isozyme protein levels and enzyme activity that vary with passage. The differences between cultured VSMCs of SHRs and WKYs do not accurately reflect those in fresh resistance and conduit vessels, either qualitatively or quantitatively. The results of VSMC culture studies should be interpreted with caution and should ideally be compared with more physiologically relevant fresh preparations.
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Authors
Zhangping Peng, William J. Arendshorst,