| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2862750 | American Journal of Hypertension | 2007 | 7 Pages |
Abstract
Folic acid prevented and partially reversed both ACTH and Dex hypertension in rats without modifying the increase in plasma F2-isoprostane concentrations. Given that BH4 failed to prevent ACTH or Dex hypertension, folic acid is unlikely to be acting through increased BH4 production. The precise mechanism for the BP-lowering effect of folic acid in this model of hypertension remains to be determined.
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Authors
Yuchun Miao, Yi Zhang, Pek S. Lim, Yada Kanjanapan, Trevor A. Mori, Kevin D. Croft, John Earl, Sze Y. Lee, Katja U.S. McKenzie, Lexian Hu, Judith A. Whitworth,