| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2862769 | American Journal of Hypertension | 2007 | 5 Pages |
Abstract
Congenic substitution mapping clarified that a chromosomal segment including the Serca II gene locus was responsible for attenuated [Ca2+]i responses and platelet aggregation in the heterozygous congenic rats. Therefore, this chromosomal region may contribute to the development of hypertension and cardiac hypertrophy by augmenting Ca2+ signaling in SHR.
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Authors
Yoichi Ohno, Yosuke Ando, Tatsuya Maruyama, Toshiyuki Morii, Takashi Eguchi, Keiichi Hirao, Tsuneo Takenaka, Yoshihiko Kanno, Hiromichi Suzuki, Takao Saruta,