| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2862790 | American Journal of Hypertension | 2007 | 6 Pages |
Abstract
Protein levels of PLC-β1 and -δ1 and PLC activity are upregulated in the systemic and renal vasculature in 6-week-old SHR, suggesting a role in exaggerated vascular reactivity during the development of genetic hypertension. A more complete understanding of the physiologic roles of PLC isozymes and their contributions to specific aspects of cellular function should advance our understanding of vascular tone/reactivity and hypertrophy/remodeling in normal and hypertensive states.
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Authors
Zhangping Peng, An Dang, William J. Arendshorst,