Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2862796 | American Journal of Hypertension | 2007 | 5 Pages |
Abstract
The results suggest that large conductance Ca2+-activated K+ channels are activated by stimulation with norepinephrine to counteract the adrenergic-induced contractions of human saphenous vein. Thus, inhibition of these channels increases significantly the contraction, an effect that appears to be mediated by an increase in Ca2+ entry through L-type voltage-dependent Ca2+ channels.
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Authors
Maria D. Mauricio, Eva Serna, Belen Cortina, Susana Novella, Gloria Segarra, MartÃn Aldasoro, Juan B. MartÃnez-León, Jose M. Vila,