Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2862997 | American Journal of Hypertension | 2006 | 7 Pages |
Abstract
Our results suggest that the carvedilol-induced decrease of blood pressure is associated with an increase of plasma NO levels. Furthermore, NOS inhibition results in impairment of carvedilol hemodynamic effects and plasma NO levels. Therefore, these results are consistent with the hypothesis that the hemodynamic effect of carvedilol is in part dependent on endogenous NO production.
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Authors
Ricardo A. Afonso, Rita S. Patarrao, M. Paula Macedo, Mota M. Carmo,