Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2898497 | Cardiology Clinics | 2009 | 9 Pages |
Abstract
Recent studies of AF have identified mutations in a series of ion channels; however, these mutations appear to be relatively rare causes of AF. A genome-wide association study has identified novel variants on chromosome 4 associated with AF, although the mechanism of action for these variants remains unknown. Ultimately, a greater understanding of the genetics of AF should yield insights into novel pathways, therapeutic targets, and diagnostic testing for this common arrhythmia.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Steven A. MD, B. Alexander MD, PhD, Patrick T. MD, PhD,