Article ID Journal Published Year Pages File Type
2951781 Journal of the American College of Cardiology 2009 6 Pages PDF
Abstract

Traditionally, assessment of coronary circulatory function has been complex, requiring invasive techniques, including quantitative coronary angiography, intracoronary flow velocity probes, and pharmacologic stressor agents. However, radiotracer-based techniques for noninvasive measurement of myocardial blood flow are now available. Studies using these new techniques demonstrate that insulin resistance is associated with functional disturbances of the coronary circulation. Conversely, insulin infusion improves coronary flow, even in the setting of type 2 diabetes mellitus and coronary artery disease.

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