Modern state of acute myocardial infarction in the interventional era: Observational case–control study—Japanese acute coronary syndrome study (JACSS)

SummaryThe Japanese acute coronary syndrome study (JACSS) is a retrospective and multicenter observational study conducted in 35 medical institutions across Japan. The JACSS database included 5325 consecutive patients hospitalized at the participating institutions within 48 h after the onset of symptoms of acute myocardial infarction (AMI) between January 2001 and December 2003. The JACSS data vividly displayed the modern state of AMI in the interventional era. Percutaneous coronary intervention (PCI) including balloon angioplasty and stent implantation was performed in 80% of the patients and approximately 90% of the treated patients had successful coronary recanalization during the acute phase of MI. The results showed very low rates of all-cause mortality and cardiovascular deaths during hospitalization. Various types of novel information have been produced from JACSS data by several leading clinical researchers in Japan and this may also be helpful in making plans for a prospective study.