Optimization of the precordial leads of the 12-lead electrocardiogram may improve detection of ST-segment elevation myocardial infarction

Leads placed on a horizontal strip, in line with leads V1 and V2, provided the optimal placement for the diagnosis of anterior and lateral STEMI and appear superior to leads V3, V4, V5, and V6. This is of significant clinical interest, not only for ease and replication of lead placement but also may lead to increased recruitment of patients eligible for revascularization with none or borderline ST-segment elevation on the initial 12-lead ECG.