Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3015916 | Revista Española de Cardiología | 2007 | 8 Pages |
Abstract
During standard therapy for preventing contrast media nephrotoxicity, (1) isotonic saline, but not hypotonic saline, increased plasma volume; (2) this increase did not raise the atrial natriuretic peptide level; and (3) no difference in the increase in serum creatinine level was observed between the two saline solutions. These findings provide evidence that 0.45% saline, at a dose suitable for preventing contrast media nephrotoxicity, is associated with a lower risk of volume expansion. This result is important for patients with severely impaired ventricular function.
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Authors
Belén Marrón, Elisa Ruiz, Cristina Fernández, Pedro Almeida, Cristina Horcajada, Felipe Navarro, Carlos Caramelo,