Article ID Journal Published Year Pages File Type
3019755 Revista Española de Cardiología Suplementos 2006 14 Pages PDF
Abstract
Dietary n-3 or omega-3 polyunsaturated fatty acids show promise as preventive therapy for cardiovascular disease, offering a safe and effective means of reducing sudden death. Oily fish is the main dietary source of omega-3 polyunsaturated fatty acid. In recent years, the anti-arrhythmic effects of polyunsaturated fatty acids have been extensively investigated. Several mechanisms that could explain these antiarrhythmic effects have been proposed and have been investigated. However, to date, no definitive mechanism has been identified. This review summarizes the epidemiological data supporting the use of omega-3 fatty acids in this context, the preclinical and clinical evidence revealed by animal and human studies, and current hypotheses about the antiarrhythmic mechanism of this class of polyunsaturated fatty acid.
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
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