| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3030535 | Trends in Cardiovascular Medicine | 2014 | 7 Pages |
Abstract
abstractThe introduction of biomimetic culture paradigms has advanced myocardial tissue engineering fundamentally, enabling today the provision of engineered rodent and human heart muscle with features characteristically found in postnatal myocardium. This is in marked contrasts to “flat” cardiomyocyte cultures with their typically low degree of organotypic maturation. Here, we discuss the collagen hydrogel-based engineered heart muscle (EHM) technology and provide background information on its use in simulations of myocardial growth and disease.
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Authors
Malte Tiburcy, Wolfram-Hubertus Zimmermann,