| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 30533 | Journal of Photochemistry and Photobiology B: Biology | 2013 | 7 Pages |
•Photo-irradiation for gold nanoparticles production using mushroom P. folorida.•Biosynthetic method is advantageous being ecofriendly and nontoxic.•Nanoparticles are characterized using UV, XRD, AFM, TEM and FTIR.•Gold nanoparticles are potential for anticancer activity in vitro.
A green chemistry approach to the synthesis of gold nanoparticles using edible mushroom Pleurotus florida (Oyster mushroom) by photo-irradiation method has been attempted. The mixture containing the aqueous gold ions and the mushroom extract was exposed to sunlight; this resulted in the formation of biofunctionalized gold nanoparticles. These nanoparticles were characterized using various techniques like UV–visible spectroscopy; X-ray diffraction studies, Energy dispersive X-ray analysis, Field emission scanning electron microscopy, Atomic force microscopy, Transmission electron microscopy and Fourier transform infrared spectrometry. The obtained biofunctionalized gold nanoparticles showed effective anti-cancer property against four different cancer cell lines A-549 (Human lung carcinoma), K-562 (Human chronic myelogenous leukemia bone marrow), HeLa (Human cervix) and MDA-MB (Human adenocarcinoma mammary gland) and no lethal effect is observed in Vero (African green monkey kidney normal cell) cell lines.
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