Article ID Journal Published Year Pages File Type
30624 Journal of Photochemistry and Photobiology B: Biology 2013 12 Pages PDF
Abstract

Three lichen extracts and ten lichenic compounds have been screened for their photoprotective activities. The determination of their Sun Protection Factor (SPF) and Protection Factor-UVA (PF-UVA) values was done in vitro. Among them, a Lasallia pustulata extract and gyrophoric acid exhibited SPF values over 5, which is better than Homosalate (SPF ≈ 4). Their photoprotective properties are only slightly modified after a 2-hours period of irradiation. Salazinic acid and L. pustulata presented characteristics of a UVA booster like the butyl-methoxydibenzoylmethane (Avobenzone) (PF-UVA ≈ 2 vs. 2.8 for Avobenzone). Salazinic acid was a better anion superoxide scavenger than ascorbic acid and none of them exhibited a photosensitizing cytotoxicity by exposing them on HaCaT cells to UVA radiations (photo-irritancy factor PIF < 5).

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Lichen extracts and compounds are evaluated for their photoprotective activities. ► Lasallia pustulata extract and gyrophoric acid are valuable UV filters candidates. ► Salazinic acid presents characteristics of a UVA booster.

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Physical Sciences and Engineering Chemical Engineering Bioengineering
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