Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3065069 | Journal of Neuroimmunology | 2009 | 7 Pages |
Abstract
In the course of Systemic Lupus Erythematosus (SLE), a variety of neuropsychiatric disturbances is reported with a prevalence ranging from 17% to 75%. The diagnosis of these syndromes is difficult and requires a careful psychiatric evaluation. Distinct autoantibodies detectable in serum or cerebrospinal fluid of patients with SLE are associated with the presence of neuropsychiatric disorders. These autoantibodies may have a pathogenic relevance in neuropsychiatric SLE or they may be merely an epiphenomenon. This review describes the various autoantibodies reported to be associated with neuropsychiatric manifestations in SLE and discusses their possible role.
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Authors
Tania Colasanti, Federica Delunardo, Paola Margutti, Davide Vacirca, Ettore Piro, Alessandra Siracusano, Elena Ortona,