| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 30731 | Journal of Photochemistry and Photobiology B: Biology | 2006 | 8 Pages |
Abstract
The photodynamic activity of water soluble mixed sulfonated metallophthalocyanines complexes: GePcSmix, SnPcSmix and SiPcSmix on human oesophageal carcinoma (SNO) cells are reported, and compared with the activity of the unmetallated H2PcSmix and of the newly synthesized water soluble adjacently substituted binaphthalo phthalocyanine (complex 3). The alkaline phosphate (ALP) showed damage to the cell membrane in the presence of complex 3 without irradiation. The GePcSmix complex caused a relatively large increase in inflammation and a high intracellular ATP.
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Authors
Itumeleng Seotsanyana-Mokhosi, Tina Kresfelder, Heidi Abrahamse, Tebello Nyokong,