Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3108444 | Critical Care Clinics | 2009 | 19 Pages |
Abstract
Infectious disease has been a leading cause of death in humans since the first recorded tabulations. From Hippocrates and Galen, to Lister, Fleming and Semmelweiss, this article reviews the notable historical figures of sepsis research. The early descriptions and theories about the etiology (microbial pathogens), pathogenesis (toxins and mediators), and treatment of sepsis-associated disease are also discussed.
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Authors
Duane J. Funk, Joseph E. Parrillo, Anand Kumar,