Article ID Journal Published Year Pages File Type
3159729 Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 2016 4 Pages PDF
Abstract

Sclerotic fibroma (SF) is a distinct benign fibrous tumor that may manifest as a sporadic solitary mass or as skin nodules in patients with Cowden syndrome. Sporadic sclerotic fibroma is an extremely rare finding in the oral cavity. In this report, we describe the first case of sporadic SF presenting on the tongue. Histologically, the tumor was a well-demarcated hypocellular nodule. The collagen fibers were densely arranged in a vague, whorled pattern with clear clefts between the collagen bundles. The immunohistochemical staining was strongly positive for vimentin and weakly positive for bcl-2. Although rare, this report confirms that SF should be acknowledged as part of the differential diagnosis of soft tissue tumors of the oral cavity.

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Health Sciences Medicine and Dentistry Dentistry, Oral Surgery and Medicine
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