Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3159888 | Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | 2013 | 6 Pages |
Abstract
Mikulicz's disease is a systemic IgG4-related condition that has recently been referred to as IgG4-related dacryoadenitis and sialoadenitis. We describe relapsed IgG4-related dacryoadenitis and sialoadenitis, so called Mikulicz's disease in a 69-year-old man who was administered with prednisolone (40Â mg/day) during March 2007. The dosage was tapered to 0.5Â mg/day over a period of 2 years with observation of the patient's clinical course. However, the bilateral submandibular and parotid glands became swollen in July 2009. A whole-body examination revealed no other illnesses or complications. A biopsy of the submandibular gland revealed IgG4-positive plasma cells. Relapsed Mikulicz's disease was diagnosed and the patient was started on prednisolone (40Â mg/day) again. At the time of writing, the patient is being maintained on 7Â mg/day of prednisolone.
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Authors
Tomoko Sugiyama, Yoshinori Jinbu, Kouichi Matsumoto, Hiroto Itoh, Tadahide Noguchi, Mikio Kusama,