Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3184332 | Alergologia Polska - Polish Journal of Allergology | 2014 | 5 Pages |
BackgroundMastocytosis is a rare disorder characterized by abnormal accumulation of mast cells in various organs. Clinical complaints include pruritus, cutaneous flushing, dyspepsia, and anaphylaxis. Symptoms are usually a result of local and systemic mast cell mediator release. The triggers include drugs, exercise, stress, anxiety, and temperature extremes.CaseWe report a case of cutaneous mastocytosis in a pregnant woman who achieved a successful pregnancy and delivered a healthy female baby.In the second case a patient with systemic mastocytosis had an unfavorable course of pregnancy that ended in extremely premature operative delivery due to fetal demise.ConclusionsMastocytosis is perceived as a medical management dilemma because of its potential for unpredictably heightened mast cell activity in response to various physiologic states including pregnancy.