Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3301680 | Gastroenterology Clinics of North America | 2007 | 19 Pages |
Abstract
Autoimmune pancreatitis (AIP) is a benign, IgG4-related, fibroinflammatory form of chronic pancreatitis that can mimic pancreatic ductal adenocarcinoma both clinically and radiographically. Laboratory studies typically demonstrate elevated serum IgG4 levels and imaging studies reveal a diffusely or focally enlarged pancreas with associated diffuse or focal narrowing of the pancreatic duct. The pathologic features include periductal lymphoplasmacytic inflammation, obliterative phlebitis, and abundant IgG4-positive plasma cells. The treatment of choice for AIP is steroid therapy. Diagnostic criteria for AIP have been proposed that incorporate histologic, radiographic, serologic, and clinical information.
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Authors
Alyssa M. MD, Amit MD, Asif MD, MBBS, Mitchell MD, Dhiraj MD, MPH,