Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
33358 | New Biotechnology | 2012 | 8 Pages |
Abstract
Recombinant proteins, in particular antibodies, have become fundamental in biomedical research where they are used in numerous therapeutic and diagnostic applications. For this reason there is an increasing demand for quick and economical production systems for recombinant proteins in mammalian cells.
► Recombinant antibodies have become fundamental in biomedical research. ► UCOE are employed for rapidly obtaining stable and highly producing cell lines. ► Using an optimized UCOE vector up to 0.5 g/l of mAbs can be produced with lab bench top device.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Sabrina Boscolo, Francesca Mion, Marta Licciulli, Paolo Macor, Luca De Maso, Martina Brce, Michael N. Antoniou, Roberto Marzari, Claudio Santoro, Daniele Sblattero,