Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3369072 | Journal of Clinical Virology | 2011 | 9 Pages |
Abstract
The emergence of oseltamivir resistance in seasonal and pandemic influenza A/H1N1 has created challenges for diagnosis and clinical management. This review discusses how clinical virology laboratories have handled diagnosis of oseltamivir-resistant H1N1 and what we have learned from clinical studies and case series. Immunocompetent patients infected with oseltamivir-resistant H1N1 have similar outcomes as patients infected with oseltamivir-susceptible H1N1. However, immunocompromised patients infected with oseltamivir-resistant H1N1 experience potentially more risks of complication and transmissibility with few therapeutic options.
Keywords
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Authors
Christian Renaud, Jane Kuypers, Janet A. Englund,