Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3370075 | Journal of Clinical Virology | 2009 | 4 Pages |
Abstract
A vaccine comprised of recombinant cytomegalovirus (CMV) envelope glycoprotein B (gB) with MF59 adjuvant developed in the 1990s recently was recently found to have efficacy for prevention of CMV infection in a phase 2 clinical trial in young mothers. This review briefly considers the rationale for gB as a vaccine antigen, the history of this CMV gB vaccine and the data supporting vaccine efficacy.
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Authors
Robert F. Pass,