Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3371261 | Journal of Clinical Virology | 2006 | 6 Pages |
Abstract
BackgroundThe association between a robust or depressed antibody response and clinical severity of SARS remains unknown.ObjectivesTo study seroconversion and the magnitude of IgG responses in a SARS cohort with different disease severities.Study design and methodA retrospective analysis of all acute and convalescent-phase sera collected from a cohort of laboratory-confirmed SARS cases. Anti-SARS-CoV IgG antibody was detected using indirect immunofluorescence technique and quantified by two-fold serial dilutions. Characteristics of patients who seroconverted “early” (
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Authors
Nelson Lee, P.K.S. Chan, Margaret Ip, Eric Wong, Jenny Ho, Catherine Ho, C.S. Cockram, David S. Hui,