Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3395204 | Anaerobe | 2013 | 4 Pages |
Abstract
During screening of human gut isolates in search of novel antimicrobials, the butyrate-producing strain Roseburia faecis M72/1 was found to produce an inhibitory substance active against Bacillus subtilis. Partial purification of the antimicrobial was achieved and activity found to be heat labile. Our findings suggest that R. faecis M72/1 produces a proteinaceous inhibitor whose production may be triggered by trypsin in the gastrointestinal tract.
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Authors
Diane Hatziioanou, Melinda J. Mayer, Sylvia H. Duncan, Harry J. Flint, Arjan Narbad,