Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3397172 | Clinical Microbiology and Infection | 2011 | 4 Pages |
Abstract
Since the diagnostic characteristics of the Check-KPC ESBL microarray as a confirmation test on isolates obtained in a routine clinical setting have not been determined, we evaluated the microarray in a random selection of 346 clinical isolates with a positive ESBL screen test (MIC >1 mg/L for cefotaxime or ceftazidime or an ESBL alarm from the Phoenix or Vitek-2 expert system) collected from 31 clinical microbiology laboratories in the Netherlands in 2009. Using sequencing as the reference method the sensitivity of the microarray was 97% (237/245), the specificity 98% (97/99), the positive predictive value 99% (237/239) and the negative predictive value 92% (97/105).
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Authors
T.N. Platteel, J.W. Cohen Stuart, G.M. Voets, J. Scharringa, N. van de Sande, A.C. Fluit, M.A. Leverstein-Van Hall,