Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3397174 | Clinical Microbiology and Infection | 2011 | 4 Pages |
Abstract
Fifty-six isolates of serotype 1 were identified during a 20-year prospective study (1989–2008), including all children with culture-proven invasive pneumococcal disease (IPD) admitted to a children's hospital in Barcelona. Forty-eight of them (85.7%) were in children aged >2 years. Complicated pneumonia (n = 28) and non-complicated pneumonia (n = 20) were the main clinical presentations. The frequency of serotype 1 IPD increased from 1999–2003 to 2004–2008: 1.2 to 4.4 episodes/100 000 children (p <0.001). The ST306 clone were identified in 70.4% of isolates. As IPD caused by serotype 1 is mainly detected in older children, a vaccination programme for children >2 years should be considered.
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Authors
C. Esteva, L. Selva, M.F. de Sevilla, J.J. Garcia-Garcia, R. Pallares, C. Muñoz-Almagro,