Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3397220 | Clinical Microbiology and Infection | 2011 | 5 Pages |
Abstract
In 2008, an increase in the prevalence of carbapenem-resistant Klebsiella pneumoniae was noted in a 286-bed tertiary case hospital in Colombia, where 84 patients (32 infected and 52 colonized) had positive cultures. The identified index patient came from Israel for a liver transplantation. High level carbapenem resistance was observed. Polymyxin B and tigecycline were the only two antibiotics that remained active. PCR-restriction fragment length polymorphism analysis and sequencing revealed blaKPC-3 in the major clone, which was indistinguishable from the K. pneumoniae carbapenemase-3-producing clone described previously in Israel. This exemplifies the threat posed by the global spread of K. pneumoniae carbapenemase-producing pathogens.
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Authors
J.A. Lopez, A. Correa, S. Navon-Venezia, A.L. Correa, J.A. Torres, D.F. Briceño, M.C. Montealegre, J.P. Quinn, Y. Carmeli, M.V. Villegasz,