Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3397326 | Clinical Microbiology and Infection | 2011 | 5 Pages |
Abstract
Thirteen carbapenem-resistant Acinetobacter baumannii isolates, collected in Romania during 2009–2010, were investigated to identify the mechanism(s) responsible for carbapenem resistance. Genotyping was performed by pulsed-field gel electrophoresis, multiplex PCR sequence typing and multilocus sequence typing. Eleven non-clonally related isolates harboured the blaOXA-23 gene on their chromosome within a Tn2008 transposon structure. The two remaining isolates harboured a blaOXA-58 gene that was either plasmid or chromosome borne. Two isolates co-expressed OXA-23 together with the extended-spectrum β-lactamase PER-1. This study constitutes the first report of OXA-58 and OXA-23-producing A. baumannii isolates in Romania.
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Authors
R.A. Bonnin, L. Poirel, M. Licker, P. Nordmann,