Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3397362 | Clinical Microbiology and Infection | 2012 | 4 Pages |
Abstract
In this retrospective observational study covering 1998 to 2008, 32 patients (mean age: 7.50 years) were identified that had 35 episodes of candidaemia (0.47 cases/1000 hospital discharges). Cancer/allogeneic haematopoietic stem cell transplantation (43%) and congenital malformations/syndromes (21%) were the predominant underlying conditions. Central venous catheterization (90%), a history of antibacterial therapy (69%) and previous bacteraemia (54%) were frequent comorbidities. Candida albicans (46%) was most common, followed by Candida parapsilosis (17%) and Candida glabrata (14%). Resistance was infrequent and limited to non-albicans Candida spp. The 30-day and 100-day mortality rates were 11.4%.
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Authors
A. Tragiannidis, W. Fegeler, G. Rellensmann, V. Debus, V. Müller, I. Hoernig-Franz, K. Siam, Z.-D. Pana, H. Jürgens, A.H. Groll,