| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3397780 | Clinical Microbiology and Infection | 2010 | 4 Pages |
Abstract
Quinolone and ß-lactam resistance mechanisms and clonal relationships were characterized among Escherichia coli isolates resistant to ciprofloxacin and extended-spectrum cephalosporins associated with human extra-intestinal infections in Rome. The E. coli. ST131 clone was found to be prevalent. This clone invariably carried a specific pattern of substitutions in the topoisomerase genes and all isolates but one produced CTX-M-15. One ST131 isolate produced SHV-12. The new ST131 variant described here is of particular concern because it combines fluoroquinolone resistance and chromosomally encoded CTX-M-15.
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Authors
M. Cerquetti, M. Giufrè, A. García-Fernández, M. Accogli, D. Fortini, I. Luzzi, A. Carattoli,