| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3398512 | Clinical Microbiology and Infection | 2008 | 5 Pages |
ABSTRACTThirty-five Bacteroides fragilis clinical isolates with varying susceptibility to meropenem were analysed with a prototype of a double-ended Etest strip containing meropenem ± EDTA, designed for the detection of the CfiA metallo-β-lactamase. Phenotypic results obtained with this new Etest strip were related to the genotype and compared to the results of the Etest containing imipenem ± EDTA. Whereas the Etest with imipenem ± EDTA only allowed detection of isolates with high-level resistance (both MICs of imipenem and meropenem >32 mg/L), reflecting the possible underestimation of CfiA prevalence in B. fragilis, the Etest with meropenem ± EDTA proved to be more accurate, particularly for isolates with low-level carbapenem resistance, suggesting its potential for broader detection of CfiA production.
