Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3399098 | Current Opinion in Microbiology | 2011 | 8 Pages |
Abstract
Although the intestinal epithelium is equipped with multiple defense systems that sense bacterial components, transmit alarms to the immune system, clear the bacteria, and renew the injured epithelial lining, mucosal bacterial pathogens are capable of efficiently colonizing the intestinal epithelium, because they have evolved systems that modulate the inflammatory and immune responses of the host and exploit the harmful environments as replicative niches. In this review we highlight current topics concerning Shigella's tactics that interfere with the innate immune systems.
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Authors
Hiroshi Ashida, Michinaga Ogawa, Minsoo Kim, Shiho Suzuki, Takahito Sanada, Claire Punginelli, Hitomi Mimuro, Chihiro Sasakawa,