Article ID Journal Published Year Pages File Type
3399255 Current Opinion in Microbiology 2012 6 Pages PDF
Abstract

Wolbachia, probably the most common animal endosymbiont, infects a wide range of arthropods as well as filarial nematodes. Generally vertically transmitted from mothers to offspring, it has evolved various strategies, ranging from brutal male-killing to mutualism, which facilitate invasion and persistence of the infections within host populations. Current interest in Wolbachia as a potential control agent against harmful nematodes and arthropods makes it important to be able to predict Wolbachia epidemiology and evolutionary trajectory. Here we highlight recent theoretical developments and suggest future modelling and empirical directions for basic and applied research in this domain.

► Wolbachia bacteria can invade arthropod populations through cytoplasmic incompatibility. ► They may also block transmission of pathogens by arthropod vectors. ► Introduction of Wolbachia to fight infectious diseases is a promising strategy. ► Theoretical models on host–Wolbachia interactions can guide release programs. ► They should be further developed to assess the sustainability of control methods.

Related Topics
Life Sciences Immunology and Microbiology Microbiology
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