Mosquito/microbiota interactions: from complex relationships to biotechnological perspectives

To date around 3500 different species of mosquito have been described, several tens of which are vectors of pathogens of remarkable interest in public health. Mosquitoes are present all around the world showing a great ability to adapt to very different types of habitats where they play relevant ecological roles. It is very likely that components of the mosquito microbiota have given the mosquito a great capacity to adapt to different environments. Current advances in understanding the mosquito–microbiota relationships may have a great impact in a better understanding of some traits of mosquito biology and in the development of innovative mosquito-borne disease-control strategies aimed to reduce mosquito vectorial capacity and/or inhibiting pathogen transmission.

► An overview of the complex relationships between mosquito and its microbiota is provided. ► We describe the impact that the microbiota has on several aspects of mosquito biological traits as nutrition, defense and development. ► We describe how these complex relationships may open perspectives for the mosquito borne diseases control.