Article ID Journal Published Year Pages File Type
3399263 Current Opinion in Microbiology 2012 12 Pages PDF
Abstract

► Botulinum Toxin (BT) may block the neuromuscular junction and the autonomic innervation of sweat, tear and salivary glands and the smooth muscles. ► This mechanism is the basis for BT's therapeutic use in a large number of medical specialties. ► BT's main indications are dystonia, spasticity, cerebral palsy, hyperhidrosis, hypersalivation, bladder dysfunction, pain and muscular wrinkles. ► Adverse effects are usually mild and always transient. BT type B may have additional systemic autonomic adverse effects.

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