Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3399483 | Current Opinion in Microbiology | 2007 | 7 Pages |
Abstract
Transfer-messenger RNA (tmRNA) enters stalled translational complexes and, with small protein B (SmpB), mediates peptide tagging of the nascent protein and release of the stalled ribosome. Recent studies clarify how the tmRNA system is targeted to ribosomes and suggest that tmRNA-tagging is used for both quality control and specific regulation of cellular physiology.
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Authors
Kenneth C Keiler,