Article ID Journal Published Year Pages File Type
3407307 Journal of Virological Methods 2010 5 Pages PDF
Abstract

Allele-specific PCR based on subtype consensus sequences is a powerful technique for detecting low frequency drug resistant mutants in HIV-1 infected patients. However, this approach can be limited by genetic variation in the region complementary to the primers, leading to variability in allele detection. The goals of this study were to quantify this effect and then to improve assay performance.

Related Topics
Life Sciences Immunology and Microbiology Virology
Authors
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