Article ID Journal Published Year Pages File Type
34098 New Biotechnology 2010 7 Pages PDF
Abstract

MicroRNAs (miRNAs) are a class of small noncoding RNAs that can regulate many genes by base pairing to sites in mRNAs. The functionality of miRNAs overlaps that of short interfering RNAs (siRNAs), and many features of miRNA targeting have been revealed experimentally by studying miRNA-mimicking siRNAs. This review outlines the features associated with animal miRNA targeting and describes currently available prediction tools.

Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
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