Article ID Journal Published Year Pages File Type
3416966 Microbial Pathogenesis 2010 6 Pages PDF
Abstract

In this study, we identified the Th epitopes in MrkD of Klebsiella pneumoniae, an excellent vaccine candidate antigen. By using the RANKPEP prediction algorithm, we have identified and characterized three Th epitopes within the MrkD antigen, which can be recognized by CD4+ T cells from BALB/c (H-2d) mice. They were M221-235, M175-189, and M264-278. These epitopes have important value for studying the immune response of K. pneumoniae infection and for designing effective vaccine against K. pneumoniae.

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